We will use an embedded mixed-methods research design, with qualitative data focusing on understanding user needs and application uptake, and quantitative data providing insights into the demand for the application and its consequences. West China Hospital surgical healthcare providers will be recruited in phase one to identify their latent need for mobile-based PAE management. A self-designed questionnaire, adhering to the knowledge, attitude, and practice framework, will be employed, and expert interviews will be conducted concurrently. To advance the project, phase two will entail the development of the integrated PAE management application and a subsequent assessment of its functional effectiveness and sustainability. Phase 3's evaluation of the total number and severity of reported PAEs will be done over two years by using Poisson regression with interrupted time-series analysis. Meanwhile, quarterly surveys and interviews will evaluate users' engagement, adherence, process efficiency and cost efficiency.
The Institutional Review Board of West China Hospital, Sichuan University, granted authorization for this study, having previously approved the study protocol, permission forms, and questionnaires (number 2022-1364). Study details will be presented to participants, and written informed consent will be secured. GW 501516 The study's findings will be made public through peer-reviewed journal articles and presentations at academic meetings.
The West China Hospital of Sichuan University's Institutional Review Board, having scrutinized the study protocol, permission forms, and questionnaires (number 2022-1364), validated and authorized the study. Participants will be given study materials, and their agreement to participate will be documented in a written form. To disseminate the study's conclusions, peer-reviewed publications and conference presentations will be employed.

To ascertain the incidence of cardiometabolic risk factors (CMRFs), target organ damage (TOD), and its contributing elements among adults residing in Freetown, Sierra Leone.
Adult participants in this community-based cross-sectional study were enrolled using a stratified, multistage, random sampling method.
A health screening study encompassing Western Area Urban, Sierra Leone, was undertaken from October 2019 to October 2021.
Enrollment saw the participation of 2394 Sierra Leonean adults, each 20 years or older.
The study encompassed a description of participants' anthropometric features, fasting lipid panels, fasting blood glucose levels, time of diagnosis (TOD), clinical histories, and demographic attributes. Cardiometabolic risks were found to be further contingent upon TOD.
In the context of known CMRFs, hypertension's prevalence was 353%, diabetes mellitus's prevalence was 83%, dyslipidaemia's was 211%, obesity 100%, smoking 134%, and alcohol consumption 379%. In addition, 161% of subjects displayed left ventricular hypertrophy (LVH) on ECG, 142% evidenced LVH on two-dimensional echocardiography, and 114% demonstrated chronic kidney disease (CKD). Diabetes and dyslipidemia significantly increased the likelihood of developing ECG-LVH, with odds ratios of 1255 (95% confidence interval: 0822 to 1916) and 1449 (95% confidence interval: 0834 to 2518), respectively. Dyslipidemia and diabetes mellitus were independently associated with a greater probability of a higher Left Ventricular Mass Index according to echocardiographic measurements (dyslipidemia OR=1844, 95%CI (1006 to 3380); diabetes mellitus OR=1176, 95%CI (0759 to 1823)). Diabetes mellitus and hypertension were both significantly correlated with a heightened risk of chronic kidney disease (CKD). The odds ratio for diabetes was 1212 (95% Confidence Interval=0.741 to 1.983), and for hypertension it was 1163 (95% Confidence Interval=0.887 to 1.525). Maximizing sensitivity and specificity via receiver operating characteristic curve analysis necessitated a low optimal cut-off point for ECG-LVH diagnosis in males (245mm) and females (275mm), as the odds of ECG-identified LVH were low.
This investigation yields novel data-driven details about the CMRF burden and its correlation with preclinical TOD in a setting where resources are limited. vaccine-preventable infection This illustration illustrates the critical need for interventions to improve cardiometabolic health screening and management within Sierra Leone's healthcare system.
Data-driven findings from this study highlight the burden of CMRF and its correlation with preclinical TOD in a setting with limited resources. This illustration accentuates the necessity for interventions in improving cardiometabolic health screening and management, specifically within Sierra Leone.

The overwhelming presence of idealized images on the internet may drive individuals to alter their physical appearance in a manner that is sometimes excessive, obsessive, and detrimental to other essential aspects of their lives. Emerging adults exhibit a diminishing regard for physical appearance, accompanied by a rising inclination toward skin-lightening procedures, often correlating with psychological distress. Examining the relationship between body image perception, skin-lightening practices, and mental well-being in Filipino emerging adults using a mixed-methods approach is the goal of this protocol, and to identify contributing factors.
The research design will involve a sequential mixed-methods methodology, with an explanatory focus. The 1258 participants in the cross-sectional study will complete an online self-administered questionnaire, whilst a case study design will comprise 25 participants undergoing in-depth interviews. Structural equation modelling, generalised linear models, and a Bayesian network will be used in the analysis of the quantitative data. In addition, the qualitative data will be analyzed thematically, using an inductive method. A contiguous narrative method will tie together the quantitative and qualitative datasets.
This protocol, having undergone review by the University of the Philippines Manila Review Ethics Board, has been approved (Reference Number 2022-0407-01). The study's conclusions will be conveyed through peer-reviewed articles and conference presentations.
The University of the Philippines Manila Review Ethics Board has validated protocol 2022-0407-01. Perinatally HIV infected children The study's conclusions will be shared with the academic community through peer-reviewed publications and conference presentations.

The application of the 'basic package+personalised package' family doctor contract model in hypertension patient management was examined in this research.
An observational approach to a study.
Within a community health center in Southwest China, the investigation took place. Data accumulation occurred consistently from January 1, 2018, to December 31, 2020, inclusive.
Hypertensive patients, specifically those aged 65, enrolled in the contract family doctor program at a community health service center in Chengdu, Southwest China, from January 2018 to December 2020, comprised the study cohort.
Key outcomes comprised average systolic and diastolic blood pressure, along with blood pressure control rates; secondary outcomes evaluated cardiovascular risk and self-management capabilities. Outcomes were measured twice: at baseline and six months following the enrollment process. Within the framework of major statistical analysis, the following methods were applied: independent samples t-tests, paired samples t-tests, and Pearson's product-moment correlation.
In the statistical analysis, the test, McNemar's test, two independent sample Mann-Whitney U tests, and paired sample marginal homogeneity tests were applied.
A total of 968 (88%) of the 10,970 patients screened for eligibility were allocated to either an observation group (receiving the 'basic package' complemented by a personalized hypertension package; n=403) or a control group (receiving only the 'basic package'; n=565), determined by the service package received. Significant differences were observed between the observation group and the control group six months after enrollment, with the former exhibiting lower mean systolic blood pressure (p=0.0023), a higher blood pressure control rate (p<0.0001), a lower cardiovascular disease risk (p<0.0001), and a higher level of self-management ability (p<0.0001). There was no statistically substantial difference in the average diastolic blood pressure between the two groups (p = 0.735).
The family doctor contract, which integrates a base package with a personalized hypertension module, yields positive outcomes in managing elderly hypertension. This leads to better average blood pressure, an increased rate of blood pressure control, a lowered level of cardiovascular disease risks, and strengthened self-management ability in the elderly.
The family doctor's contract service, structured with a 'basic package' and a 'hypertension' add-on package, effectively tackles elderly hypertension. This model shows positive effects on average blood pressure, the rate of blood pressure control, the level of cardiovascular disease risk, and the self-management skills of elderly patients.

Analyzing how the utilization, traits, and effect of local health counselors affect the decisions to seek treatment among adults residing in Nigerian slums.
A pre-tested questionnaire was utilized in this cross-sectional study.
Two communities, plagued by poverty, are found in Ibadan, Nigeria.
This study's demographic analysis examined 480 working adults, specifically those aged 18 through 64.
During their recent health issues, 400 out of 480 respondents (83.7%) had conversations with at least one lay advisor. The personal networks of family and friends were instrumental in contacting a total of 683 lay consultants. Among the respondents, none included details about online network members or platforms in their responses. A considerable majority, roughly nine tenths of the population, engaged in conversation with a lay consultant concerning a health matter, without any particular support sought. Yet, a significant proportion (680 out of 683, or 97%) of the contacted lay consultants furnished some kind of backing.